Lung fibrosis – Communicable Diseases Research

Efficacy and safety of Treamid in the rehabilitation of patients after COVID-19 pneumonia: a phase 2, randomized, double-blind, placebo-controlled trial

Article

Published on 2022-11-032022-11-16
Journal: Journal of Translational Medicine
[Category] 비임상,

Identification of the effects of COVID-19 on patients with pulmonary fibrosis and lung cancer: a bioinformatics analysis and literature review

Article

Published on 2022-09-262022-11-15
Journal: Scientific Reports
[Category] SARS, 바이오마커,

Attenuation of SARS-CoV-2 replication and associated inflammation by concomitant targeting of viral and host cap 2′-O-ribose methyltransferases

Article

Published on 2022-09-012022-11-15
Journal: The EMBO Journal
[Category] COVID19(2023년), SARS, 치료제,

Circulating microRNA signatures associated with disease severity and outcome in COVID-19 patients

Article

Published on 2022-08-112022-11-15
Journal: Frontiers in Immunology
[Category] SARS, 치료제,

[키워드] 95% CI adaptive immune responses Angiogenesis antiviral response antiviral responses asymptomatic infection AUROC Biomarker Biomarkers chemokines circulating miRNA clinical condition collected Combination COVID-19 COVID-19 pathogenesis COVID-19 patient DE miRNA death differentially expressed disease disease severity downregulation driven by experiment Genes healthy control heart failure highlighting Hospital admission human cell impairment in vitro induce Inflammation inhibit Innate immunity interferon involved leukocyte life threatening Lung disease Lung epithelial cells Lung fibrosis microRNA microRNA. Mild miR-4433b-5p miRNA miRNA signature miRNAs moderate modulated Mortality organ damage outcome Patient predicted pro-inflammatory cytokine pro-inflammatory factors provided RNA-sequencing SARS-CoV-2 SARS-COV-2 infection Sensitivity and specificity serum serum sample severe COVID-19 severe disease severity Stress subset the cytokine storm upregulation Vascular damage was performed with COVID-19
[DOI] 10.3389/fimmu.2022.968991 PMC 바로가기

Residual lesions on chest-Xray after SARS-CoV-2 pneumonia: Identification of risk factors

Case Reports

Published on 2022-05-132023-07-06
Journal: Medicina clínica
[Category] COVID19(2023년),

[키워드] chest X-ray coronavirus disease Enfermedad por coronavirus Fibrosis pulmonar Lung fibrosis Radiografía de tórax.
[DOI] 10.1016/j.medcli.2021.04.001 PMC 바로가기 [Article Type] Case Reports

Inhibition of lung microbiota-derived proapoptotic peptides ameliorates acute exacerbation of pulmonary fibrosis

Research

Published on 2022-03-232022-10-05
Journal: Nature Communications
[Category] 바이오마커, 유전자 메커니즘,

Potential “Therapeutic” Effects of Tocotrienol-Rich Fraction (TRF) and Carotene “Against” Bleomycin-Induced Pulmonary Fibrosis in Rats via TGF-β/Smad, PI3K/Akt/mTOR and NF-κB Signaling Pathways

Article

Published on 2022-03-052022-10-31
Journal: Nutrients
[Category] COVID-19, MERS, SARS,

[키워드] administration alteration Anti-inflammatory antioxidant Apoptosis approach Bacterial biochemical BLM candidate carotene caused collagen Combination demonstrated develop disease downregulated downregulation drug Effect expressions Factors fibrosis fraction functions genetics histopathological histopathological finding hydroxyproline increased expression Inflammatory cytokine influences inhibit injection interstitial investigated Lung fibrosis Lung injury lung tissues management modulation molecular NF-κB NF-κB signaling Pathways post-COVID-19 patient Potential preventive effects Probability proinflammatory cytokines provided pulmonary pulmonary fibrosis rapid progress RAT reduction in reported shown significantly tocotrienol-rich fraction treated Treatment TRF upregulation variety viral infections
[DOI] 10.3390/nu14051094 PMC 바로가기 [Article Type] Article

Diethylcarbamazine as potential treatment of COVID-19 lung fibrosis

Correspondence

Published on 2022-03-012022-10-05
Journal: Medical Hypotheses
[Category] 신약개발, 치료법,

[키워드] Anti-inflammatory antiparasitic drug clinical study coronavirus disease COVID-19 COVID-19-related pulmonary fibrosis Diethylcarbamazine Drug repurposing immunomodulatory activities Lung fibrosis post-COVID-19 Potential treatment pulmonary fibrosis treat
[DOI] 10.1016/j.mehy.2022.110774 [Article Type] Correspondence

Lung Function, Radiological Findings and Biomarkers of Fibrogenesis in a Cohort of COVID-19 Patients Six Months After Hospital Discharge

Research article

Published on 2022-02-012022-10-05
Journal: Archivos de bronconeumología
[Category] 바이오마커,

[키워드] 6 minute-walk test 6-MWT6 minute-walk test 95% CI 95%CI acute respiratory distress syndrome age ARDSacute respiratory distress syndrome Biomarker BMIbody mass index body mass index change changes in Chest CT Chest radiography chronic obstructive pulmonary disease circulating Computed tomography COPDchronic obstructive pulmonary disease Coronavirus disease 2019 correlation COVID-19 COVID-19coronavirus disease 2019 CT scan CTComputed Tomography diffusing capacity for carbon monoxide diffusion discharge discharged patients DLCOdiffusing capacity for carbon monoxide elevated evaluate Factor female Fibrogenesis finding function functional GGOground-glass opacity Ground glass opacity ground-glass opacity HFNChigh flow nasal cannula oxygen high flow nasal cannula oxygen ILDinterstitial lung disease impairment IMVmechanical ventilation Interstitial lung disease involved lesion lung Lung fibrosis matrix metalloproteinases mechanical ventilation MMP1 MMP7 MMPmatrix metalloproteinases mMRCmodified British Medical Research Council modified British Medical Research Council Month multicenter NIVnon-invasive ventilation non-invasive ventilation parenchymal Patient patients with moderate performed Peripheral blood proportion prospective observational cohort pulmonary pulmonary fibrosis Pulmonary function test radiographic assessment of lung edema radiological radiological abnormality RALEradiographic assessment of lung edema respiratory parameters Result reverse transcriptase-polymerase chain reaction RT-PCRreverse transcriptase-polymerase chain reaction SARS-CoV-2 pneumonia SARS-CoV-2severe acute respiratory syndrome coronavirus 2 SARSSevere Acute Respiratory Syndrome sEGFRsoluble epidermal growth factor receptor serum biomarker serum biomarkers Severe acute respiratory syndrome severe acute respiratory syndrome coronavirus 2 Severe COVID-19 pneumonia severe patients Sex soluble epidermal growth factor receptor Survivors vascular endothelial growth factor VEGFvascular endothelial growth factor
[DOI] 10.1016/j.arbres.2021.08.014 [Article Type] Research article

The possible role of ursolic acid in Covid-19: A real game changer

Research article

Published on 2022-02-012022-10-05
Journal: Clinical nutrition ESPEN
[Category] COVID19(2023년), SARS, 신약개발, 임상, 치료제,